Inductive determination of allele frequency spectrum probabilities in structured populations
نویسندگان
چکیده
منابع مشابه
Universality of fixation probabilities in randomly structured populations
The stage of evolution is the population of reproducing individuals. The structure of the population is known to affect the dynamics and outcome of evolutionary processes, but analytical results for generic random structures have been lacking. The most general result so far, the isothermal theorem, assumes the propensity for change in each position is exactly the same, but realistic biological ...
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A forward diffusion equation describing the evolution of the allele frequency spectrum is presented. The influx of mutations is accounted for by imposing a suitable boundary condition. For a Wright-Fisher diffusion with or without selection and varying population size, the boundary condition is lim(x downward arrow0)xf(x,t)=thetarho(t), where f(.,t) is the frequency spectrum of derived alleles ...
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One of the main necessities for population geneticists is the availability of statistical tools that enable to accept or reject the neutral Wright-Fisher model with high power. A number of statistical tests have been developed to detect specific deviations from the null frequency spectrum in different directions (i.e., Tajima’s D, Fu and Li’s F and D test, Fay and Wu’s H). Recently, a general f...
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ژورنال
عنوان ژورنال: Theoretical Population Biology
سال: 2019
ISSN: 0040-5809
DOI: 10.1016/j.tpb.2018.10.004